The asset pricing models CAPM Essay Example | Topics and Well Written Essays - 1000 words

The asset pricing models CAPM - Essay Example For instance, if investor A buys more of stocks of X than Y, then every investor in the market will react the same by buying of stocks X and less of Y. Therefore, from this illustration and the aforementioned explanation, it is evident that the two models assumes that the investors in the market evaluate the information they have in the same way, hence arriving at the same decisions regarding their investment activities. However, given that investors have homogeneous expectations concerning their returns, level of risk inherent and investment strategies, they will always tend to remain risk averse (Sharpe, 1964). From the explanation above, it is clear that the models of APT and CAPM depend on the publicly available information concerning the returns and level of risk inherent in specific securities (Watson and Head, 2007). Therefore, the models do not specify any particular information that investors should use regarding their investment decisions but assume the investor will use the most current information available in the market concerning the different securities, thus, helping them choose the best investment strategies. The proponents of the APT argue that the model is the best alternative to the CAPM because it has more assumptions requirements that are flexible (Reilly & Brown, 2011). For instance, whereas the capital asset pricing model uses the expected return of a security, APT uses a security’s risk expected return, in addition to, the risk premiums of a couple of macro-economic elements. Therefore, from this proposition it is undeniable that CAPM has more strong assumptions compared to the APT. For instance, whereas the CAPM assumes that there exists a risk free rate in the market, the APT model tries to identify risk premium to enable investors take advantage of any mispriced securities, which is different from the

The Kissnger Qiestion Essay Example for Free

The Kissnger Qiestion Essay The Vietnam War resulted in the deaths of 1.5 million to 3 million Vietnamese and other Indochinese and 58,000 Americans. It was the catalyst for Richard Nixon’s self-induced disgrace. Henry Kissinger played a pivotal role in guiding America’s foreign policy as the war torn nation reeled under the loss of one president to assassination and another to fraud. The Vietnam War singed the conscience of the world and Kissinger found himself where foreign policy and national security converged. National Security Advisor is the one that holds the most strategic meetings at the highest levels of US administration. External and internal threats to the nation’s security and well being should be calculated well in advance; otherwise the entire fabric of security planning lies in shreds. There must have been some constructive and sensible proposals to avert the Vietnam fiasco. It’s fair to ask what alternative course Americas critics would have followed. Some serious people argued for complete withdrawal, on the grounds that the war was already lost. Some have argued that Nixon, after taking office, should have declared that the situation in Vietnam was far worse than he had thought, blame it on the Democrats and seek a deal with the North Vietnamese like the one that was ultimately reached. Meanwhile, the argument goes, Nixon could have used tough rhetoric at home to appease the foreign policy makers. Whether the approach would have worked can’t be known, but had it worked, it certainly would have been preferable to what happened instead. Once in office, Kissinger and Nixon said they were seeking peace with honor: the abandonment of our South Vietnamese allies would be a dishonorable betrayal and would undermine our credibility in the world. America ended up abandoning them anyway. Even overlooking for the moment how the whole thing turned out, the peace with honor formulation was riddled with flaws. And the South Vietnamese regime was known to have been inept and hopelessly corrupt. In writing about the importance of our allies in South Vietnam, Kissinger gives minimal attention to the Vietnamese people but a great deal to South Vietnam’s president Nguyen Van Thieu, calling him a great patriot and a dauntless leader. McNamara and Kissinger, not unlike some American presidents, including Nixon, had myopic affinity for strongmen like the Shah of Iran, Philippines president Ferdinand Marcos. A student of Metternich, the 19th-century Austrian statesman, Kissinger was a practitioner of the realist (or realpolitik) school of diplomacy, which places emphasis on the state’s interests and the use of military power to achieve them, and he preferred to deal with the strong leaders of nation-states who could deliver. The US administration’s complicity in the 1963 overthrow of South Vietnam’s leader General Ngo Dinh Diem conferred legitimacy on the North Vietnamese claim that the South Vietnamese government was illegitimate. Ironically, when all this was happening in Vietnam, the rest of the world could only look and expect. Even the Nobel society that conferred the peace prize to Kissinger made almost no mention of the American lives lost during the Vietnam War, and none of the fact that USAs pursuit of what many saw as a patently hopeless cause may have damaged Vietnam permanently. To see the US side of the story, Nixon had a peculiar governing style. He hated to give direct orders and sometimes issued orders he hoped or expected would not be carried out. He had an aversion to controversy among his advisers. And after Vice President Spiro Agnew said in one meeting that the South Vietnamese, with American support, should attack two North Vietnamese sanctuaries in Cambodia rather than just one, as had been proposed, Nixon agreed. But, according to Kissinger, Nixon was so annoyed that Agnew had staked out a more hawkish position than his own that he excluded Agnew from the next meeting on the war. Even Kissingers colleagues are portrayed as politically astute Mel Laird, secretary of defense, to be slippery. Though, Laird was often proved right about the likely public reaction to proposed U.S. actions. Unfortunately, the men surrounding the president were accomplished charmers, masterly manipulators in a field where manipulation was the job requirement. The Vietnam War was not without its tragicomic aspects. There was the futile hunt for the elusive COSVN, supposedly the North Vietnamese military headquarters in Cambodia—and a leading rationale for U.S. military incursion into Cambodia in 1970. The South Vietnamese troops and their American advisers found only deserted huts. Nevertheless, USA describes the attack as a success, leading to the capture of documents, arms and ammunition, which, according to Karnow, were quickly replaced. There was also the raid by American commandos on the Son Tay prison in North Vietnam, which was believed to hold American prisoners of war but turned out to be empty. U.S. intelligence had said the prison was closed. The war did infuse sacrifice, though not entirely based on moral lines. Historians omit several relevant matters or deals with them in triumphs of understatement. The two senior members of the National Security Agency, Anthony Lake and Roger Morris, quit in 1970 in protest over the expansion of the war into Cambodia. And as for the national upheaval and constitutional crisis that was Watergate, Nixon felt unappreciated for his effort to withdraw troops, that antiwar sentiment touched Nixon on his rawest nerve and that he saw enemies all around him and so engaged in methods of all-out political combat. That’s it. No mention of Nixon’s enemies list; of the White House’s hiring a goon squad (the plumbers) to conduct break-ins; or of Kissinger’s supplying names to the FBI for wiretaps of his own aides and of journalists, to trace leaks about the war. Vietnamese people had to face brutalities of warring factions and deceit of their power hungry leaders. Many years on, we still cannot confidently classify the leaders who could have been true to the national cause or the people of Vietnam. Some critics persisted in believing that given enough time and resources, Americas Vietnam policy would have succeed. In 1975, after Ford had taken office as president with sole card to prevent Saigon’s collapse was additional money from Congress to fund the war effort—an appropriation that Congress was resisting. The denial of the money may well have sped the collapse of the South Vietnamese government, but how long it could have been sustained is another matter. If leaders truly continued to believe in enforcing the type of government, one is forced to conclude that USA would have deluded the world. Kissinger and Nixon were in a bunker of their own, clinging to the false promise of Vietnamization, holding to a misbegotten concept of national honor and railing at the war’s opponents. Great nations have the intent to make the right decisions in critical circumstances. Unfortunately, the reputation of USA is doomed to carry the fact that they failed to take a timely decision in Vietnam. References    John Prados, LOST CRUSADER: The Secret Wars of CIA Director William Colby, Oxford University Press, 2003

Validity is important to the research process

Validity is important to the research process Sim and Wright, (2000:125) stated that, Validity relates to the truthfulness of data and requires independent knowledge of the true nature or magnitude of the entity. Clinical research scientists are much aware of the need for validity in their research. Validating the treatment is important to determine the efficacy of a treatment as well as effectiveness and the treatment provided and its outcome. It is learnt that in 1957, American Social Scientist Donald Campbell introduced the concepts of internal validity and external validity. The study has an internal validity, when the result of a study demonstrates the existence of a causal relationship between the independent and dependent variables. Campbell and Stanley, (1963) noted that the internal validity is the basic required accuracy for any experiment. On the other hand, the external validity refers to the extent to which the results of a study or the experiments are made applicable to the population from which the participant in the experiment is drawn. Similarly, as Thomas and Nelson, (1990) noted that the external validity is about the generalizability of the findings. The first part of this essay will discuss the concepts of internal validity and external validity, the causal effect of variables and extraneous variables with examples. In the second part, the essay will critically evaluate the implication of internal and external validity and their relationship. Due to word constraint this essay will focus only on the quantitative research. The experimental (explanatory) research concerned with cause and effect by its nature, internal validity can be discussed within the frame work of quantitative research. Furthermore, Thomas and Nelson, (1990) stated that the cause and effect can be determined by the use of good research knowledge to the experiment design. According to Judd, et al., (1991, cited in French, et al., 2001:16) the internal validity concerns the extent to which conclusions can be drawn about the casual effects of one variable on another. For example, the treatment or a cause (independent variable) such as moist heat which effectively relieves the symptoms of low back pain or an effect (dependent variable). Before establishing a cause-effect relationship, it is important to find the relationship between the treatment and the symptom. The argument is that when treatment is given, the relief in pain (outcome) is observed, but when no treatment is given no outcome is observed. This provides the evidence that, the treatment and the outcome are related. However, it does not provide the evidence that the particular treatment caused the outcome. Perhaps, it may be some other factor caused the outcome rather than the treatment. For example, if the subjects were on pain relieving medication and medication may be the confounding factor in relieving the symptoms of low back pain. If the pain relieving medication factors are not controlled, they will have a confounding influence on the independent variable which threatens the internal validity. However, sometimes it is important to emphasize that the confounding variables cannot be fully controlled. The researcher assumes that there is a casual relationship in the study and claims that, research findings have implication for other groups and individuals in other settings and time. These claims examine the external validity. Polit and Beck, (2008) stated that the external validity is a major concern in quantitative research where there is a diffic ulty in generalizing the result from controlled research settings to real clinical practice settings. For example, findings about a pain relieving treatment in a study of African women cannot be generalized to women in Australia. Finally, it is a researcher decision to design a study to enhance the external validity. The potential threats to the internal validity are history, maturation, testing, instrumentation, statistical regression, selection error and mortality. Threats to the external validity are, selection, setting and time. A few threats are discussed in the following example. A randomised control trial study was conducted by Deyle, et al., (2000), to evaluate the effectiveness of physical therapy for osteoarthritis of the knee. The study concluded that a combination of manual physical therapy and supervised exercise yields functional benefits for patients with osteoarthritis of the knee and may delay or prevent the need for surgical intervention. Even though confounding variables were controlled in this study by using randomisation, treatment and placebo groups, the researcher could not overcome with the threats like maturation and other extraneous variables. During the intervention patients were also on medication and exercises. They were asked to contact the researcher after one year of the intervention for the feedback. The researcher failed to explain whether intervention caused the effect or the medication or due to result of the passage of time. Simultaneously this study lacks the generalizability due to the fact that patients had to have sufficient English language skills and were required to live within a one hour drive from the clinics. Portney and Watkins, (2009:162) stated that, extraneous variables can be controlled by the experimenter by manipulating the independent variable, by random assignment of subjects to the groups and by using a control or comparison group within the design. Masking or blinding is also be used in many quantitative research studies to prevent the bias and to strengthen the internal validity. The external validity can be strengthened by selecting the sample which represents the population and there by applying the findings to a broader group. Similarly in the representative of clinical settings where the study takes place and th e findings can be applied to strengthen the other settings. It was stated by Polit and Beck, (2008) that multisite study results are confident enough in attaining the generalizability, if the results have been replicated in several sites where the study involves a heterogeneous sample. The relationship between the internal validity and external validity refers to the famous researchers Campbell and Stanley, (1963) statement that, often external validity sacrificed if the researcher concentrates on the internal validity. It is learnt from the literatures that, many researchers have given importance to the internal validity in their studies. However, in an applied area of clinical research, the purpose is to improve the health of the public and it is also important that the external validity be emphasized and strengthened. It is true that, the researcher implements more control measures to increase the internal validity, the experiment will become more artificial and thereby the external validity suffers or decreases. Cronbach, (1982) argued that, if a treatment is expected to be relevant to a broader context, the causal inference must go beyond the specific conditions. If the study lacks generalizability, then the so-called internally valid causal effect is useless to decision makers. Polit and Beck, (2008) noted that there are many differences between the countries in methods of diagnosis and management, as well as important racial differences in susceptibility to disease and natural history of the disease. Differences between health-care systems can affect the external validity. In an article, Efficacy and Effectiveness Trials (and Other Phases of Research) in the Development of Health Promotion Programs Flay, (1985) proposes a model that emphasizes the internal and external validity at different stages of the research process and that would lead to the translation of research to practice. In a controlled experiment like randomized control trials of public health interventions, efficacy trials have a high internal validity but often have the liability of low external validity. But, effectiveness trials have a high external validity. Historically, researchers have tended to focus on maximizing the internal validity. The idea is that the inter ventions should work under highly controlled conditions than its implication to the different population groups, organizations, or settings. Similarly, Polgar and Thomas, (2008) noted that funding organizations and journals have tended to be more concerned with the scientific rigor of intervention studies than with the generalizability of results. The consequence of this emphasis on internal validity led to lack of attention to and information about external validity, which has contributed to the researchers failure to translate the study into the general population. Thus, the progress from efficacy trials to effectiveness trials has not become a reality because of the time and cost involved in the process of research to practice. As a result of the failure of this model, practitioners are often unable to determine whether the given studys findings can apply to their local setting, population or resources. However, there are several reasons for the lack of information on external va lidity being an important contributor to the failure to translate research into public health practice. Policy and administrative decision-makers are unable to determine the generalizability or breadth of applicability of research findings. In addition Hamersley, (1991) criticised that the distinction between the internal and external validity is fundamentally misleading because it reflects a failure to distinguish relations between events and relations between variables. Polit and Beck, (2008) noted that in the recent studies researchers are interested in promoting designs that aim to achieve a balance between internal and external validity in a single intervention study. Such practical (or pragmatic) clinical trials or studies attempt to maximize external validity with the smallest possible negative effect of internal validity. For example, Thomas, et al., (2006) conducted a study on randomised control trial of short course of traditional acupuncture compared with usual care of pe rsistent non-specific low back pain. The study concluded that referral to a qualified traditional acupuncturist for a short course of treatment seems safe and acceptable to patients with low back pain. However, the generalizability of this study finding rests on the assumption that participating acupuncturists, general practitioners, and patients in York are similar to those found elsewhere. According to Polit and Beck (2008), in health care research RE-AIM framework has been formed by Russell. E. Glasgow in 2006 to design and to evaluate the intervention research. It involves a scrutiny of five aspects of study like, reach, efficacy, adoption, implementation and maintenance. It may help in improving the generalizability of the research study or enhance the external validity. An Importance of an internal validity or the external validity is a controversial topic in the research community. Campbell and Stanley, (1963) stated that, a good study should be strong in both types of validi ty. The internal validity is indispensable and essential while the question of external validity is never completely answerable. In other words, Campbell and Stanleys statement implies that the internal validity is more important than the external validity. However a study with no external validity still found true relationship for the sample that was studied. For example, if the researcher conducts a study on Bangladeshi farmers in the Afghan region, the findings of the study cannot be generalize to the Chinese horticulturist in the Malaya region. But researcher still knows more about the Bangladeshi farmers. In conclusion, it is understood that, the internal validity and the external validity plays an important role in the scientific research. The internal validity establishes the truth about inferences regarding cause-effect or causal relationship. The external validity establishes the truth of conclusion that involve generalisation. As internal and external validity are fundamental to any experimental research, the researcher should aware of threatening factors. In quantitative research, the use of randomisation and the control groups reduces the threats to internal validity. Meanwhile, sample selection and settings in the research helps in controlling the threats to external validity. The strength of internal and the external validity of a study can help researchers to evaluate the relative importance of that study in an overall program of research. To balance the validity, researcher should conduct a study that emphasizes the internal validity (efficacy studies) and undertake effecti veness studies that emphasize the external validity. The internal validity and the external validity are important to building an evidence based study in the clinical research. A clear definition of concepts involved in the experiment not only ensures its validity, but also increases the chances that it could be used by other researchers wishing to carry out a follow-up or similar investigation.

Death Penalty :: essays research papers

This paper will fallow the process of a capital trial from arrest to execution. It will discus the aspects of federal and state law, trial, appeal, and executions. It will go into further detail on arraignment and the trail details of defense and sentencing. The federal law on capital punishment begins with the constitution, which states in the eighth amendment of the bill of rights that, no person shall be subject to cruel or unusual punishment. Despite this and for the reason that it is the government that decides what is cruel and unusual, capital punishment is still federally legal. Under the united states code, title eighteen there are certain crimes that can be punished by death. Section thirty-four of the said title and code says that any crime that results in the death of any person can be punished by death. Section 1512 deals with witnesses, victims, or informants. It states that anyone who kills or atemps to kill another person with the intent to prevent the attendance or t estimony at trail may be punished by death. Section 2332 states that who ever kills a national of the united states while the national is outside the united states is subject to death if the killing is murder as it is defined. Section 36 states that participants in any continuing criminal enterprise dealing with controlled substances may be punished by death. Section 1992 states that whoever willfully derails, disables, or recks any train used in interstate or foreign commerce can be punished by death. Finally section 831 states that anyone involved in prohibited transactions involving nuclear material can be subject to the death penalty. State laws in capital punishment defer from state to state and vary in a wide range of crimes for which it can be imposed. This range usually contains one or more of the fallowing, murder of a law enforcement officer, vehicular homicide while under the influence, contract killings, felony murder, first degree murder, or any murder. No matter the la ws of the state are certain states have and will always use their own discretion in handing down a death sentence. This means that for what ever reason, be it social make up, religious make up, or the simple fact that a death sentence may inhibit the prosecution, in that the jury may be hesitant to take a life no matter what the crime, the death sentence is not always used in all cases that it is allowed in.

Hamburger and Perfect Party Food Essay

I hate when my stomach feels so empty. The growling and tightening of my insides drives me insane. The only thing on my mind at the time is food. Anything else doesn’t matter. My three favorite foods are chicken, burgers, and last pizza. You can’t go wrong with chicken. It goes with many sides such as corn, potatoes, or fries. Fried chicken is the best because it makes the skin so crisp and crunchy. If I had to choose out of my top three foods chicken would most likely be number one. Second choice that I have named is burgers. The best hamburgers are the ones that come straight off of the bar -b- que pit. Usually for summer we always have burgers because they are the easiest things to make and they also go well with birthdays or holidays. The lettuce, ketchup, mustard, tomatoes, etc. all make the hamburger so delicious. Last we have pizza. My favorite type of pizza is pepperoni because it is so good. If I have to choose any other toppings I would choose meat lovers because it’s all different types of meat on one pizza. They seem to be the perfect party food because I usually order them when I don’t feel like leaving the house or when my friends and I are having a small get together. What would we do without food? Having a nice full stomach makes you happy and it also gives you energy. Food will always be something that I will cherish in life, especially my favorite three that I mentioned earlier in my essay. Food is a very important thing and I have lots of other favorites.

How did religion influence the fabric of colonial life? Essay

Increased autonomy in the hospital interns of the budget. These include decisions like what and how much to spend on staffing and drug purchases. Performance should be used in rewarding management team. This will encourage the team to make more sound judgments and implement better policies. Increased budget for drugs and any other medical supplies. When the budget is adjusted positively, the hospital will be at a position of buying more drugs, this will encourage quality care and utilization rate; in terms of the number of admissions. At the long run, this decreases the total cost per admission. Changing Normal practices for specific admission cases. This is through physicians of different departments of the hospital. When this is put into practice, the length of stay will be reduced by more than 50%. The reduction of stay realizes a decrease in the cost. Level of competency should also be increased in terms of staffing ratios per bed, supporting technology, team work and services rendered by the organization are all determinants of the quality of services. An upgrading formula encourages changes and efficiency. For instance, patients at ICU will tend to need more patients than patients at orthopedics. Maintenance of hospital equipments. Normally, maintenance of hospital equipments in majority of US hospitals today, maintenance is mainly focused of repairing hospital equipments that have already been confirmed as out of order. But it doesn’t take maintenance to prevent future damage seriously. If preventive measures are taken, this will reduce the cost of future spending. What should cost containment programs focus on? Maximizing available funds for budgets’ sake. This can be done through four ways one is through Medicare maximization. A couple of states may be service providers but some of these funds are got through general funds. Such should be converted to become Medicare programs. This in return adds on revenue through increased federal funds. Switching from low match to high match categories is another way the government can gain by receiving enhanced reimbursement for services that are already provided. Government should also focus in inter-governmental transfers. This focuses on lending to less advantaged sectors of the economy by the sectors that are doing fine. Containment programs should also focus on reconfiguring the long term Care delivery system. This encourages community and home cares for status since they are able to cut Medicare spending or also provide more effective and attractive services. This requires more focus on the long term demand for long term care services. Considering how expenditures for prescription drugs moved up, focus should be directed to states that cover outpatient prescription drugs under Medicare. They must cover necessary cost with the government to pay taxes for the product they purchase. The state should also perform management benefits included for people with more drug costs. The state also focuses on adjusting reimbursement rates for specific services to containment strategy. Managing health care better: This can involve Primary Care Case Management (PCCM) or conventional managed care. People should work hand in hand with the state to improve the quality of a care given. In addition the federal government should also focus on expanding managed care. The government should encourage Movements like Medicare. Selective contrasting is the last form of focus that the federal government should consider. The government can turn to selective contracting or let people be involved in competitive bidding in order to cut cost. (Kala 2002) What Should Be Done In Order To Reduce Cost Inefficiency Hospitals should not be let to run independently and if they have to, the government should run majority of the hospitals and the private sector be left to run a similar percentage to cut monopoly that gives entrepreneurs the right to increase hospital costs. â€Å"Like many businessmen of genius he learned that free competition was wasteful, monopoly efficient. And so he simply set about achieving that efficient monopoly† (Mario Puzzo 1920) The government should introduce rules and regulations that manage the hospitality industry at large. If the federal government monitored the spending and introduced rule that doctors should follow they will have no reason to ignore. the general public too will know that they are obliged to do a particular task. For instance ignorance of the general public is encouraging exploitation because they are turning to insurance companies. Insurance companies on the other hand have realized that there is a big opportunity to maximize profits due to the linking of hospital costs. If the general public decides to ignore insurance or have their terms and conditions stated first, then insurance companies will cut cost too. Government spending should be monitored. In cases where any particular government introduces a particular monetary policy, spending is automatically regulated. If the USA government introduced a fiscal or monetary policy, Different sectors of the economy can be taxed more in order to reduce the difference; for expansion and sales. An example is the drug companies and insurance companies. Bibliography Appleby J (2007) Consumer Unease with US health care grows.USA Today. Garman N. & Tyler. J. (2004), CEO Succession planning in freestanding US hospitals: final report. American College of healthcare executives. Golda D, Richard R, Latha M: (2005). Containment in the intensive care unit. The internet journal of pulmonary medicine: Puzzo (1969) US Novelist. The Godfather Ladenheim Kala (2002) Medicaid Cost Containment: legislation’s tool kit. Fried H Productive, (1998) Scale and scope efficiencies in US hospital-bases nursing homes Patrick M, Rosko M, Vaidmanis v . Relationship between hospital cost inefficiency and debt ratings.

Kandinskys Improvisation 28 What Lurks Beyond the Abstract

Kandinskys Improvisation 28 What Lurks Beyond the Abstract Abstract art has definitely shaken the world, reinventing people’s perception of what reality is (Walther, 2000); and, talking about abstract art, Kandinsky and his daring experiments should be mentioned first. By far the most famous, the most frequently researched and the most often misinterpreted, his Improvisation 28 deserves a close attention.Advertising We will write a custom essay sample on Kandinskys Improvisation 28: What Lurks Beyond the Abstract specifically for you for only $16.05 $11/page Learn More Despite the fact that the chaos depicted in the artwork is typically attributed to the horrors of the World War I, it can be assumed that the artist’s goal was to display not the pointless bloodbath that the WWI was, but the atmosphere of complete denial and total loss of hope that swung in the air since the World War I broke out. Even being a specimen of an abstract art, Kandinsky’s work still has all the properties of a traditio nal artwork. However, some of these properties have been stretched to their furthest extremes, therefore, making the painting look almost grotesque and yet managing to convey the despair that the Improvisation 28 is shot through with. For example, the line is very smooth in the composition; neither or the elements has any sharp edges or simply looks clumsy – every single line is drawn in a nonchalant yet smooth manner. Another formal element worth a discussion is the color cast. On the one hand, the work looks unusually colorful for expressing the despair and sorrow that gripped the world after the WWI. Indeed, taking a quick look at the painting is enough to see that Kandinsky’s choice of colors is very versatile. With yellow, green and blue being the focus of the picture, and a touch of the red color to mark the edges and add the impression of flickers of fire, or, perhaps, a dawning day, the picture might seem rather optimistic. However, the gloomy, almost grayish s hades that Kandinsky uses in his painting suck all the liveliness out of the picture, therefore, making one think of the hopes that used to be so daring and yet were killed so mercilessly. Hence the use of another formal element, i.e., light, stems. With a number of spots left empty on the white canvas, Kandinsky managed to keep the light out of the picture as hard as possible therefore, hinting at the probable post-apocalyptic results of the WWI for the entire humankind (Aronov, 2006). As a result, Kandinsky made a very wise use of space, cluttering the elements that are supposed to symbolize the outcomes of the WWI and leaving considerable white space at the bottom of the picture. Thus, the emptiness, which the bloodbath of the WWI resulted in, was shown to the audience.Advertising Looking for essay on art and design? Let's see if we can help you! Get your first paper with 15% OFF Learn More The structure of the artwork is rather peculiar. On the one hand, there is no clear symmetry in the painting; every single element has its own unique shape and role in the artwork. However, together, these elements see, weirdly harmonic. For example, the two picture planes that the right prolonged elements split the artwork in, make the painting look especially organic. The line drawn from the upper right side of the picture into the horizon also contributes to understanding the structure of the picture better. The texture of the picture is rather standard. By using oil on canvas, Kandinsky managed to create a truly outstanding work of art. Finally, one must say a couple of words about the composition of the painting. As it has been stressed, the work is split into three parts, i.e., the cluttered left side, a more spacious right side and the horizon, which has been painted in blazing red. It seems that the aforementioned elements represent the chaos (the left side), the devastation and emptiness that the WWI has left the humankind to (the right s ide), and the unclear future (the upper right corner). As it has been stressed above, the key historical context of the Impression 28 is the concept of the World War I as one of the most, if not the most devastating and horrendous events that have ever taken place in the world history. One of the key reasons why the given artwork differs so much from the rest of the portrayals of the WWI, especially the use of smooth lines, can be explained by Kandinsky’s life experience. As Gardner and Kleiner explain, â€Å"Born in Russia, Vassily Kandinsky (1866– 1944) moved to Munich in 1896 and soon developed a spontaneous and aggressively avant-garde expressive style† (Gardner Kleiner, 2009, 386). Therefore, it can be assumed that the Slavic origin, combined with the experience in Germany and, therefore, resulting in both denial of the Nazi movement and the feeling that he was still a part of it, led to Kandinsky developing a very unusual, sharp and emotionally unstable, almost to the point where it turned into a grotesque, painting style: â€Å"Artists, Kandinsky believed, must express the spirit and their innermost feelings by orchestrating color, form, line and space† (Gardner Kleiner, 2009, 692). Improvisation 28, thus, seems the utter manifestation of the given style, Kandinsky’s most successful attempt at portraying his denial of the Nazi policy and the fear of the post-WWI world, with its devastation and the death of all hopes for further development. In some respect, however, Kandinsky’s work can be considered the product of its time. It would be wrong to claim that Kandinsky was the only artist who used the â€Å"lineless† and â€Å"shapeless† manner of painting at the beginning of the XX century. As Selz explained,Advertising We will write a custom essay sample on Kandinskys Improvisation 28: What Lurks Beyond the Abstract specifically for you for only $16.05 $11/page Learn More The first decade of the twentieth century saw European art moving along a number of fronts in the general direction of an art without representational imagery – toward an art purely of colors, lines and shapes that bore no direct relationship to the appearance of the outside world. (Selz, n. d., 421). That being said, one must admit that there is much more to the artwork than most people see in it; the chaotic elements are supposed not to express a specific event in history, even such grandeur one, as the WWI, but to embrace something even more overwhelming, like the spirit of lost hopes that had been soaring in the air since the beginning of the XX century (Knapp, 2000). These were not the acts of violence occurring during the WWI that Vassily Kandinsky focused on, but the moods in the society that drove people to committing these acts of violence. In other words, Improvisation 28 is not supposed to express the artist’s idea about the tendencies in the society at the beginning of the XX century. The painting expresses the turmoil, the fears, the anxiety and the despair of the humankind at the beginning of the new century, making the audience experience every single emotion, which makes the painting unbearably true and amazingly grotesque at the same time. Reference List Aronov, I. (2006). Kandinsky’s quest: A study in the artist’s personal symbolism, 1866–1907. New York, NY: Peter Lang. Gardner, H. Kleiner, F. S. (2009). Gardner’s art through the ages: A concise global history. Stamford, CT: Cengage Learning. Knapp, S. (2000). The contemporary thesaurus of search terms and synonyms: A guide for natural language computer searching. Phoenix, AZ: The Orys Press.Advertising Looking for essay on art and design? Let's see if we can help you! Get your first paper with 15% OFF Learn More Selz, P. (n. d.). The aesthetic theories of Kandinsky and their relationship to the origin of non-objective painting. Retrieved from https://msu.edu/course/ha/240/selzkandinsky.pdf Walther, I. F. (2000). Art of the 20th century. Vol.1. Koln, DE: Taschen.

NHS

NHS Most juniors and seniors aim for graduating with a diploma. Obtaining a high school diploma may be important for a graduates future education, perpetuate job as well as his/ her income for living.Colleges require a diploma in order to enroll into the school. Specific colleges required higher diplomas. For instance, a person plans on attending the University of Virginia or Harvard Law School, which requires an advance diploma as well as a spectacular grade point average. Attending college will control the out come of ones future. The area one majors in depends on the college they enroll their self into.A satisfying job requires a high education from college. The importance of a person's job leads toward their future. Which corresponds to what he/she does for a living. Providing money for them to survive off of. Without a good job, they have a low possibility of them being capable of supporting his/her self and maybe even their family.Photograph of front facade, Austin Hall, Harvard L. ..A person would probably be bereft later in life. Compare a doctor's salary and education opposed to a cash registers salary and education. Obviously the doctor has a better job and is more opulent because of the higher salary and a higher education. A person jeopardizes his/her future without an education. So don't start off your life unkempt!When you graduate from high school you definitely want a diploma. Why go through all those years without getting a purpose out? Just the sensation of accomplishing all four years of high school! Majority of parents muse and want their kids to graduate high school with a diploma. Just the extraordinary sensibility of walking down the aisle as they call out your name. Throwing your hat in the air at the same time as your fellow classmates. Wouldn't you want to...

Auditory system and optical system Essay Example for Free

Auditory system and optical system Essay Two of the most important sensory systems in human body are optical system and auditory system. Optical system or sometime called visual system involved in the process of taken amount of stimuli and transfer it into some figure that we can perceive as images that make senses. Auditory systems involved in sound wave that transduced by drum ear into some kind of vibration that eventually gets converted back into wave what we perceive as noise. There are a lot of similarities in their mechanisms of how they gather, carry and prepare those informations from sensory neurons. However, there are also a lots of differences on how each system operated and where does it takes information into difference area of the brain. For both systems, optical and auditory, the information comes from our environment in many forms. For example, optical system detected all still images and image in motion as far as human eyes can see. The auditory is ready to absorb any noise or sound for twenty-four hours a day. Their structures and mechanisms are similar in a way they gather information, prepare and perceive those information into something that make sense in our brain. After the sensory neurons carry information into specific system each detect, transduce and coding those information before they being send to central system, the brain. Both systems have similar structure that transmit those information to the final destination, the brain. Even though, both system basic the same. Each system perceive those information that perceive from sensory neuron in totally different way. For instance, optical system receive visible spectrum of wave of electromagnetic radiation. The frequency of wave created color and distinguish brightness by amplitude. In auditory system, the frequency of wave created tone ( pitch) and loudness by amplitude. For the optical system, the cornea gather light rays that pass into inferior of the eyes. The information such as light’s brightness, hue/color or motion are translate into coded neural impulse. The codes then carried by optic nerves to the brain. However, the information from one side are send to the opposite side of hemisphere but stimuli go to the same side hemisphere. The optical information are stored in occipital lobes where it was process and try to make sense of those information base on experience and individual perception. For the auditory system, the sound’s wave goes through the ear canal and hit the ear drum. They activate the the drum and the information being send through the fluid as a result it bents the hair cell in the cochlea and the information then translate into neural impulse. The intensity of sound waves determine by how many hair cell are fire as well as how frequently they fire. The auditory information then carried by auditory nerve from one side of the ear are sent to the opposite hemisphere. The auditory information are stored in temporal lobes where it was process and try to make sense of those information base on past experience and pattern. In conclusion, the optical and auditory systems have basically the same structure and mechanism but they both different in how they gathering, preparing, detecting, and translating those information. Each system are unique and unbelievably complex structure that we need to learn more. Auditory system and optical system. (2016, Jun 17).

Outlined based on the questions Essay Example | Topics and Well Written Essays - 1500 words

Outlined based on the questions - Essay Example This paper will focus on the Roman, the British, and the Third Reich empire and how they handled their computer administration systems (Black, 2002). The Roman Empire The Ancient Roman Empire began its history as a city-state. The early Roman Empire culture was unique and had a significant influence on the Western world. Rome is known to be an empire that conquered many territories around the Mediterranean Sea. Rome grew into a huge empire because of how it applied technological concepts and ideas in its activities. Roman Empire had powerful administration systems that it used to handle information of individuals and the cities it conquered. This empire would then use the information to give citizenship to the people of those cities (Black, 2002). Roman Empire applied its technologic systems in recruiting its army and administrative purposes such as in voting. Roman Empire relied on agriculture to drive the economy. The infrastructure was made using stone, sand and marrum, which is, still used today where a multi-layering technique was used to ensure stability of the road. Therefore, the ideas and concepts of the Roman Empire are still in use4 today only that modern administrative systems are used today. The Roman Empire had a significant influence on the Western World and continues to do so today (Black, 2002). ... For example the First Generation computers (1951–1959) were made using vacuum tubes as the storage device. Subsequent developers would advance on this original work by replacing various hardware components in order to deliver a more faster and powerful Product. An example is the work of Charles Babbage who was a British mathematician, inventor, philosopher, and mechanical engineer. Babbage invented the first programmable computer that eventually inspired more complex designs such as the abacus. Another example is The Manchester Small-Scale Experimental Machine (SSEM), that is also referred with the term â€Å"Baby† (Black, 2002). This was the world's first stored-program computer and although initially it was not meant to be a practical computer, it was actually meant for a test bed for Williams Tube, which is the earlier memory device. Baby was built by Frederic C. Williams, Geoff Tootill and Tom Kilburn at the Victoria University of Manchester in the early 1950s was a powerful administrative system with many functions in the British empire owing to its ability of rapid manipulation of numbers (Black, 2002). After the development of Baby, the subsequent computing hardware devices were developed and categorized into various â€Å"generations† based on the technology that would be used. Third Reich The Third Reich,  is the official Nazi designation for in Germany dating from January 1933 to May 1945, and presumed as the official successor of the medieval and early German Empire from 1871 to 1918 referred as the Second Reich. The IBM and the Holocaust book tells the story of IBM's conscious or direct involvement or through its subsidiaries in the Holocaust. Besides this, the book tells of IBM’s involvement in the Nazi

Zines. Zine World Essay Example | Topics and Well Written Essays - 750 words

Zines. Zine World - Essay Example Zines covers culture remote the corporate restrictions. They evaluate and criticize other zines, books, comics, newsletters, one-shots, videos, posters, spoken word recordings, or anything else in almost any media on any subject. Their focus is on material that's not available through normal commercial channels, so readers find reviews of hundreds of hand-made magazines, newsletters, and books you won't find anywhere else. Every review includes ordering information, so reacders can get this material direct from its publishers. Zine World is an example of a zine as well as Punk Zine. In addition to the reviews, Zine World covers news nobody else does: When publishers are brought up on charges for what they've published, when kids are kicked out of school for creating a zine, they try to spread the word, letting our readers know what they can do to help. In every issue of Zine World, small publishers let each other know which stores and distributors are trustworthy, and which aren't. They run free announcements about upcoming events, and other underground projects worthy of readers' support. They offer free classified ads for DIY or counterculture projects (up to 50 words; limit one free ad per issue). (Bartel, 2004) If the writers published something, and they are wondering how to get the word out to potential readers, these budding writers can consider sending it to Zine World. They are interested in almost anything that isn't corporate-controlled crap. Zine Wold's pledge -- to themselves, to their readers -- is that they'll give everything a fair read and an honest review. Their circulation is tiny, but they have been told that a good review can result in dozens of orders. The Punk zine offers discussions about rock music from its origins and up to the artists. They believe that the origins of Rock music can be explored through the attempts to understand the natural development of musical styles. A musical genre such as rock and roll does not simply come out of the music scene. It evolved from the moment a performance introduces a breakthrough which the audience perceived and admired due to its uniqueness. The best thing about rock music, according to Punk Zine, is that it is not limited to being a musical genre but some even consider it as a way of life, it is also known as a movement, a lifestyle, a culture and has the possibility of being an ideology. Rock and roll is a tradition and in its many faces can be considered a belief system. The premise of the work in the Punk Zine is that rock 'n' roll matters, and that it means what it says. It seems that rock 'n' roll music has seldom been given its due as an art form, that it is somehow relegated to a category of less "mature" or "serious" artistic pursuits by the media and the intellectual community (whatever that is). Some of their critics use the generic term "Pop" to refer to any popular music, including all contemporary rock musicians, as if the fact of rock 'n' roll's immense commercial success implies that it cannot really be taken seriously alongside, say, classical music, or even Jazz. In defiance of this trend (Zines), and in view of the apparent retreats from idealism that have permeated the past decade or two, these zines celebrates creative writing as a legitimate art form, and more, as a strong current in American and world culture, which contains a central

Gun laws Essay Example | Topics and Well Written Essays - 1000 words

Gun laws - Essay Example Specifically, the events of the Aurora, Colorado theater shooting alongside the Sandy Hook Elementary School massacre have galvanized public opinion on both sides of the issue. As such, this brief analysis will seek to consider the debate from the perspective of the pro-gun control movement. In such a way, it will be the express goal of this author to relate to the reader some of the most powerful arguments in favor of further gun control and the rationale behind these. As such, it is the author’s hope that the reader will gain a more nuanced and complete understanding of the main arguments for further gun control by an analysis of the following 4 arguments: the Second Amendment does not, nor did it ever, provide for individual gun rights, the high rate of gun related violence and death, as well as the societal needs for reasonable gun control laws, and whether or not further testing should be put in place for those individuals that have a propensity to instability. Finally, a n examination of an even more vehement argument with regards to gun control will be entertained and discussed. The first, and perhaps most contentious of the issues that this analysis will seek to discuss, is the issue of whether or not the Second Amendment to the United States Constitution sought to convey individual gun rights to the citizen. ... In such a way, the Second Amendment can and should be interpreted as little more than admission from the Federal government that it promises not to infringe upon the rights of the militias (National Guard and Army Reserves) to maintain a stock of weaponry for the purpose of defense and securing the borders of the new nation. This particular argument hinges upon interpretation of the Constitution; one of the most contested documents within the political spectrum (Saenz 1). However, from a rhetorically honest standpoint, the text of the bill specifies specifically what it denotes; i.e. the right of the states and by extension the militias under their control to retain weapons. In short, such argument is valid; however, it cannot be used to effectively engage those members of the pro-gun persuasion due to the fact that they have almost invariably chosen to interpret the document by a wholly different standard (Trotter 26). The second argument which will be utilized within this brief ana lysis is the fact the extraordinarily high rate of gun crime and the increasingly gruesome nature that it has taken within the past several years demands stricter gun laws. There have always been cases of extreme violence, even massacres, within American society; however, the fact of the matter is that almost all of these hideous crimes have a single factor in common; the widespread and pervasive use of semi-automatic weapons, readily obtained by individuals who can easily be described as unstable, as well as the implementation and usage of high capacity magazines (Shear 1). Whether or not guns should be allowed is not the central issue that is up for debate; rather, the issue at hand is the ease and availability that is unilaterally shared by almost all of the purveyors

Let Me Say It Essay Example | Topics and Well Written Essays - 250 words

Let Me Say It - Essay Example Moreover, the family and the society is always engaging to bring out the best among family members (Kragen). It has been observed that the continuous communication maintain cohesion among nation and where there is breakdown of interpersonal communication there are tension that lead to conflict. Moreover, the process of communication is influenced by what one says (Interpersonal Communication and Personality). The respondent analyses the message he receives and respond to it appropriately (Kragen). ‘Interpersonal communication is irreversible’ (Kragen). Once people act or communicate to other people it is not possible to erase or reverse the process. For example when a person send out an email it is not possible to withdraw what has been sent. Moreover, it is impossible to forget peoples behaviors learned through communication exchanges. Furthermore, it is impossible to undo an act or unsee things already seen. The communication process in interpersonal communication cannot be restarted and presenting a new version of a story does not erase a previous good or bad episode. Therefore, what people communicate become a behavioral sequence of interpersonal communication

Lerning orgnistion Case Study Example | Topics and Well Written Essays - 5500 words

Lerning orgnistion - Case Study Example In this context, the key str'tegic m'n'gement question is, wh't strengths must 'n org'niz'tion develop to rem'in relev'nt 'nd competitive' This contextu'l shift, implies th't the competitive 'dv'nt'ge, even surviv'l, of enterprises depends on their 'bility to le'rn f'ster th'n their competitors 'nd to 'pply or embed le'rning in systems, processes, 'nd pr'ctices. It is underst'nd'ble th't concepts such 's 'ction le'rning, te'm le'rning, org'niz'tion'l le'rning, work-b'sed le'rning 'nd cross-cultur'l le'rning h've become ' centr'l focus. It is the purpose of this p'per to 'ssist in bridging the g'p by suggesting ' pr'ctic'l 'ppro'ch to workpl'ce le'rning th't is linked with org'niz'tion'l objectives 'nd integr'ted with project m'n'gement. The p'per develops the models of org'niz'tion'l le'rning 'nd work-b'sed le'rning 's well 's provides the discussion of differences in these two 'ppro'ches. The b'rriers to work-b'sed le'rning 're covered in the c'se study th't critic'lly demonstr'ted the 'ppro'ch of org'niz'tion'l le'rning 'nd project-b'sed le'rning on the ex'mple of p'rticul'r org'niz'tion. This p'per h's two p'rts. ... e, even surviv'l, of enterprises depends on their 'bility to le'rn f'ster th'n their competitors 'nd to 'pply or embed le'rning in systems, processes, 'nd pr'ctices. It is underst'nd'ble th't concepts such 's 'ction le'rning, te'm le'rning, org'niz'tion'l le'rning, work-b'sed le'rning 'nd cross-cultur'l le'rning h've become ' centr'l focus. It is the purpose of this p'per to 'ssist in bridging the g'p by suggesting ' pr'ctic'l 'ppro'ch to workpl'ce le'rning th't is linked with org'niz'tion'l objectives 'nd integr'ted with project m'n'gement. The p'per develops the models of org'niz'tion'l le'rning 'nd work-b'sed le'rning 's well 's provides the discussion of differences in these two 'ppro'ches. The b'rriers to work-b'sed le'rning 're covered in the c'se study th't critic'lly demonstr'ted the 'ppro'ch of org'niz'tion'l le'rning 'nd project-b'sed le'rning on the ex'mple of p'rticul'r org'niz'tion. This p'per h's two p'rts. P'rt ' suggests ' model for project-b'sed workpl'ce le'rning th't integr'tes work 'nd le'rning with theory 'nd pr'ctice within ' project m'n'gement fr'me. This 'ppro'ch dr'ws on the liter'ture rel'ting to c'p'bility, org'niz'tion'l le'rning, 'nd project m'n'gement. P'rt B is ' c'se study of the 'pplic'tion of this 'ppro'ch in 'n British public sector 'gency. The lessons le'rned m'y be 'pplied in other settings 'nd 'lso provide opportunities for focused rese'rch on org'niz'tion'l le'rning. P'rt ': ' Model of Project-B'sed Workpl'ce Le'rning 1. Org'niz'tion'l le'rning 't le'st three dilemm's 're r'ised by the liter'ture on org'niz'tion'l le'rning: whether to develop ' le'rning org'niz'tion before developing org'niz'tion'l le'rning; whether to invest consider'ble le'd time to develop (or 'd'pt) the preconditions 'nd co-requisites for effective

Gun laws Essay Example | Topics and Well Written Essays - 1000 words

Gun laws - Essay Example Specifically, the events of the Aurora, Colorado theater shooting alongside the Sandy Hook Elementary School massacre have galvanized public opinion on both sides of the issue. As such, this brief analysis will seek to consider the debate from the perspective of the pro-gun control movement. In such a way, it will be the express goal of this author to relate to the reader some of the most powerful arguments in favor of further gun control and the rationale behind these. As such, it is the author’s hope that the reader will gain a more nuanced and complete understanding of the main arguments for further gun control by an analysis of the following 4 arguments: the Second Amendment does not, nor did it ever, provide for individual gun rights, the high rate of gun related violence and death, as well as the societal needs for reasonable gun control laws, and whether or not further testing should be put in place for those individuals that have a propensity to instability. Finally, a n examination of an even more vehement argument with regards to gun control will be entertained and discussed. The first, and perhaps most contentious of the issues that this analysis will seek to discuss, is the issue of whether or not the Second Amendment to the United States Constitution sought to convey individual gun rights to the citizen. ... In such a way, the Second Amendment can and should be interpreted as little more than admission from the Federal government that it promises not to infringe upon the rights of the militias (National Guard and Army Reserves) to maintain a stock of weaponry for the purpose of defense and securing the borders of the new nation. This particular argument hinges upon interpretation of the Constitution; one of the most contested documents within the political spectrum (Saenz 1). However, from a rhetorically honest standpoint, the text of the bill specifies specifically what it denotes; i.e. the right of the states and by extension the militias under their control to retain weapons. In short, such argument is valid; however, it cannot be used to effectively engage those members of the pro-gun persuasion due to the fact that they have almost invariably chosen to interpret the document by a wholly different standard (Trotter 26). The second argument which will be utilized within this brief ana lysis is the fact the extraordinarily high rate of gun crime and the increasingly gruesome nature that it has taken within the past several years demands stricter gun laws. There have always been cases of extreme violence, even massacres, within American society; however, the fact of the matter is that almost all of these hideous crimes have a single factor in common; the widespread and pervasive use of semi-automatic weapons, readily obtained by individuals who can easily be described as unstable, as well as the implementation and usage of high capacity magazines (Shear 1). Whether or not guns should be allowed is not the central issue that is up for debate; rather, the issue at hand is the ease and availability that is unilaterally shared by almost all of the purveyors

Lerning orgnistion Case Study Example | Topics and Well Written Essays - 5500 words

Lerning orgnistion - Case Study Example In this context, the key str'tegic m'n'gement question is, wh't strengths must 'n org'niz'tion develop to rem'in relev'nt 'nd competitive' This contextu'l shift, implies th't the competitive 'dv'nt'ge, even surviv'l, of enterprises depends on their 'bility to le'rn f'ster th'n their competitors 'nd to 'pply or embed le'rning in systems, processes, 'nd pr'ctices. It is underst'nd'ble th't concepts such 's 'ction le'rning, te'm le'rning, org'niz'tion'l le'rning, work-b'sed le'rning 'nd cross-cultur'l le'rning h've become ' centr'l focus. It is the purpose of this p'per to 'ssist in bridging the g'p by suggesting ' pr'ctic'l 'ppro'ch to workpl'ce le'rning th't is linked with org'niz'tion'l objectives 'nd integr'ted with project m'n'gement. The p'per develops the models of org'niz'tion'l le'rning 'nd work-b'sed le'rning 's well 's provides the discussion of differences in these two 'ppro'ches. The b'rriers to work-b'sed le'rning 're covered in the c'se study th't critic'lly demonstr'ted the 'ppro'ch of org'niz'tion'l le'rning 'nd project-b'sed le'rning on the ex'mple of p'rticul'r org'niz'tion. This p'per h's two p'rts. ... e, even surviv'l, of enterprises depends on their 'bility to le'rn f'ster th'n their competitors 'nd to 'pply or embed le'rning in systems, processes, 'nd pr'ctices. It is underst'nd'ble th't concepts such 's 'ction le'rning, te'm le'rning, org'niz'tion'l le'rning, work-b'sed le'rning 'nd cross-cultur'l le'rning h've become ' centr'l focus. It is the purpose of this p'per to 'ssist in bridging the g'p by suggesting ' pr'ctic'l 'ppro'ch to workpl'ce le'rning th't is linked with org'niz'tion'l objectives 'nd integr'ted with project m'n'gement. The p'per develops the models of org'niz'tion'l le'rning 'nd work-b'sed le'rning 's well 's provides the discussion of differences in these two 'ppro'ches. The b'rriers to work-b'sed le'rning 're covered in the c'se study th't critic'lly demonstr'ted the 'ppro'ch of org'niz'tion'l le'rning 'nd project-b'sed le'rning on the ex'mple of p'rticul'r org'niz'tion. This p'per h's two p'rts. P'rt ' suggests ' model for project-b'sed workpl'ce le'rning th't integr'tes work 'nd le'rning with theory 'nd pr'ctice within ' project m'n'gement fr'me. This 'ppro'ch dr'ws on the liter'ture rel'ting to c'p'bility, org'niz'tion'l le'rning, 'nd project m'n'gement. P'rt B is ' c'se study of the 'pplic'tion of this 'ppro'ch in 'n British public sector 'gency. The lessons le'rned m'y be 'pplied in other settings 'nd 'lso provide opportunities for focused rese'rch on org'niz'tion'l le'rning. P'rt ': ' Model of Project-B'sed Workpl'ce Le'rning 1. Org'niz'tion'l le'rning 't le'st three dilemm's 're r'ised by the liter'ture on org'niz'tion'l le'rning: whether to develop ' le'rning org'niz'tion before developing org'niz'tion'l le'rning; whether to invest consider'ble le'd time to develop (or 'd'pt) the preconditions 'nd co-requisites for effective

Sustainability Development in Hotel Industry Essay Example for Free

Sustainability Development in Hotel Industry Essay Hotel industry in recent past has come up with various sustainable development measures. These measures are from conserving water, waste management , energy saving to creating green room. The industry has integrated its business with Sustainable development approach in various functions such as Operations, supply Chain and procurement. These sustainable approaches has benefited industry in terms of cost and brand. This research paper find out how globally Hotel industry is adopting sustainable development approaches in the daily business. The goal of Sustainable Development is clearly to secure economic development, social equity and environmental protection. As much as they could work in harmony these goals sometimes work against each other in our modern world. The rapid development of good living, travel and in general of the consumer society has often resulted in less protection to the environment and to some groups of the world population. Ferocious search for profitability has not co-existed harmoniously with making the world a better place. However there is a general consensus that t cannot go on for ever and those who are favored by life now feel responsible for those who have not had the same chance. Economic growth will always remain the basis of human development but it should integrate as well its impact on the people and on the planet. SD focuses on having a holistic approach to development taking into consideration economic, social and environmental needs while avoiding over utilizing key natural resources. Hospitality or Hotel industry all over the world is leading in creating sustainable model for other industry. Area of S ustainable Developments in Hotel industry Water As the hotel industry is a large consumer of water it is obvious that it should demonstrate its concern about this major problem. Currently, in a lot of hotels, guests are recommended to keep their towels –sometimes their sheets- for more than a day in order for hotels to conserve water and reduce the use of detergent. It is a worthwhile undertaking but one that sounds hypocritical as it appears to be as a cost saving exercise. Energy The installation of fluorescent lights throughout a hotel reduces energy consumption by thousands of dollars as does the replacement of windows. Green roofs help conserve energy. New energies – wind, solar should be encouraged. Not only these programs help save energy but they cut maintenance costs. Their pay-back period is generally very good. Governments usually encourage the efforts by giving grants or tax cuts. Hotel companies should do whatever can be done to help develop clean energies. Waste There is an enormous amount of waste in the hotel industry and particularly in the food industry. A significant global project is to engage the units to reduce waste as much as possible and to recycle it Greenhouse Gas emissions (GHG) Hotels, using major quantities of energy, produce major quantities of GHG. The measurement of the reduction of GHG emission is more visible when consolidated at company level. A company can make a pledge to offset carbon emissions by supporting an organization such as Climate Care. Paperless environment When one considers the quantity of paper that is used in a hotel one cannot but think of the destruction of trees and its impact on global warming. Moreover the printing of paper is often totally useless and people often discard papers after a meeting or will not even look at them at a later point. When one adds the production of ink and toners to supply photocopy machines it is easy to realize the negative impact of such habits on the environment. In a computerized world it is evident that old habits should be discouraged. Not only would it help the environment but it would also cut costs dramatically in the long term. Only the necessary printing of paper and strict use of recycled paper should be encouraged. Green Hotel Program – A new Concept In an industry where investment in the end product (rooms) is enormous it is significant to spend money wisely with a focus on the environment. It actually ives a great opportunity for the company to display its commitment to SD. Every aspect of room construction and decoration can be addressed: flooring, wall-covering, air conditioning, electrical installation, water usage, furniture, textile and equipment. Clearly the process should not only consider the room but the whole property; however in the hotel industry it is the room product that captures the attention of the public Procurement The value chain of the hotel industry includes a major component which is procurement. This is true not only during construction but while running a hotel and a restaurant. This activity will reveal how a sound hotel SD policy can have a ripple effect on other industries, engaging the procurement company and all suppliers in the same direction. Vendors involved in a hotel construction and renovation program should be made aware of the objective of the company. Moreover the procurement company should include Sustainable Development in its own strategy. It can start with presenting as many green products as possible and encouraging vendors to reduce packaging and offer recyclable products. It should as well emphasize buying sustainable food only. Once the procurement company is involved in this mission it will encourage hoteliers to go yet further in their SD efforts. The purchasing power of a procurement company is enormous and it will help reduce the unit price of sustainable products as they can be more expensive than non-sustainable products and it discourages hoteliers and restaurateurs from buying SD products. A major endeavor for a procurement company is to include Fair Trade in its strategy enabling local suppliers to develop their business and helping poor countries to expand their economy. It should not however stop companies from considering Fair Trade as a great opportunity to improve their corporate social responsibility. Industry Standards for ‘Green Hotel’ According to US green building council a ‘Green’ or ‘Sustainable’ Hotel will : †¢Use 26% Less Energy †¢Emit 33% Carbon Dioxide †¢Use 30% Less Indoor Water †¢Send 50%-75% less Solid Waste to Landfills and Incinerators †¢Green Buildings can also encourage the use of alternative transportation (walking, mass transit, low-emission, fuel-efficient or alternative fuel vehicles) World Wide Leading Hotels in Sustainable Development Fairmont Hotels Resorts Fairmont is certainly the hotel company that has introduced Environment and Community Service earlier than others in its global strategy. Due to its history and its hotels locations, often in the countryside, the company has officially recognized the importance of Environment in 1990 and pioneered the Fairmont Green Partnership, in order to minimize the impact of its hotels on the planet. It encourages all properties to individually search for environment initiatives, be it minimization of pesticide on their golf course, encouragement to use hybrid cars, etc. Its main topics are waste reduction, resource conservation, purchasing policy, habitat and species protection and community connection. They encourage as well Social Responsibility through the Fairmont Hotels Resorts charitable donations program that delivers grants which support Education and Youth development programs, Health programs, Social services and Civic and community projects. Through these programs Fairmont has received many accolades and awards, most recently the WTTC Tourism for Tomorrow 2006 award. Accor As of today Accor is the hotel company that is the most advanced in its SD approach. It started as an Environment strategy in 1994 building a network of 53 environment correspondents throughout the world. Sustainable Development was officially embedded in the strategy of the company in 2002 with the appointment of a Director of Sustainable Development, member of the Management Board, the creation of a group-wide SD committee and the development of an exhaustive SD strategy. That strategy encompasses all aspects of the concept. A scorecard has been developed that checks Accor’s involvement throughout the world with all takeholders: Shareholders, Customers, Employees, suppliers, Environment and local communities. The company was one of the first ones to sign the Global Compact initiative launched by UN Secretary General, Kofi Annan, in January 1999 which is a commitment to follow strict guidelines in terms of Human rights, Labor, Environment and anti-corruption initiatives. Accor is not only focused on developing a group SD strategy but insists in reaching each and every one of its 170 000 employees through direct campaigns. It sends a strong message to all employees by published a short document highlighting conservation tips, a comic book about environment conservation, and an environment guide for hotel managers to train their employees about all aspects of environmental protection. A SD purchasing charter was developed and distributed to suppliers to entice them to follow SD guidelines and involve them in a virtuous circle. Environment and eco-efficiency start during the development phase of all projects. The Company uses internationally or nationally recognized certifications. 0 hotels are now ISO 14001 certified and more certifications are in the pipeline. In Canada its hotels are Audubon certified for eco-efficiency. Measurements are in place to show the energy, waste and water consumption reduction. Biodiversity and architectural integration are another focus in the development of projects. For international and shareholder recognition Accor is listed in the major socially responsible investment indexes: DJSI World Stoxx, FTSE4Good, ASPI and ESI indexes. InterContinental Hotels Group IHG has evidently undergone a major shift toward a complete Sustainable Development strategy recently. The basis is there to make it the industry reference in the coming years. The group will not only be the largest hotel company in the world but as well, naturally, can become the most admired one. All components of SD have been addressed. Many actions geared toward social responsibility and environmental protections have been endorsed throughout the years by various divisions or hotels and coordination is now taking place. Measurements will help demonstrate that the company walks the talk and a separate and comprehensive company SD report will position the company not as one of but as the hotel company that leads the industry. It would be convenient to â€Å"brand† this strategy so that all could refer to it easily. A Senior Vice President Global Corporate Social Responsibility position was created in September 2006. Hilton Hilton Corporation has not yet embraced a holistic approach to Sustainable Development. They communicate mostly on Corporate Social Responsibility (CSR) and Environment concerns. Their CSR is focused on four areas: Education programs Selected Healthcare programs Youth programs Civic affaires and Public policy. Their Environment policies are based on a tagline: Reduce Reuse – Recycle. The company was the first in the industry to be awarded the EnergyStar award (US) for its involvement in reducing electrical energy consumption –fluorescent bulbs in all areas-, water conservation – towel program-, recycling. It encourages its employees to be involved in various community services. Hilton International (now bought by Hilton Corp) has started a program called We Care which is addressing mostly environmental issues and community service. They have included it in their balance scorecard system. Hilton Hotels has developed an interesting program to help improve relationship between people: Be Hospitable Kimpton Hotels It has divided its operations into two distinctive divisions: Hotels and Restaurants. It is very much involved in Sustainable Development and Environmental protection. Kimpton EarthCare: Their mission statement is the following: â€Å"To lead the hospitality industry in supporting a sustainable world, by continuing to deliver a premium guest experience through non-intrusive, high quality, eco-friendly products and services†. One of these initiatives is the creation of an eco-friendly room at the Triton hotel in San Francisco designed to become a best practice for the company. It offers amenity dispensers – to reduce packaging waste-, energy efficient lighting and motion sensors, non-toxic environmentally safe products, eco-friendly paints, energy efficient mini-bars and air conditioning system, etc. Kimpton’s SD strategy is clear, with a twist of being specific to â€Å"boutique/hip hotels†. However there are still at the initial stage when it comes to measurements. Some of them are the following: â€Å"Over $500,000 in new revenue attributed to EarthCare Over 12,000 gallons (over 360 bathtubs) of toxic cleaners removed from our water supply Conserved over 103,000 gallons of water at Hotel Allegro, Chicago Hotel Monaco Salt Lake City awarded the e2 environmental award Galleria Park Hotel in San Francisco saved $4,000 from just changing Exit lighting to LEDs†. Six Senses SPAs Their purpose: â€Å"To create innovative and enriching experiences in a sustainable environment†. They have an exhaustive list of values all geared towards the happiness of their staff and customers: â€Å"epitomizing all senses: sight, sound, smell, taste, touch †¦ and beyond†. Their environmental program is developed in the Holistic Environmental Management Program. Being generally located on tiny islands, their goals are: to reduce resource consumption and waste generation. to manage energy use and water conservation. o hire members of local communities and engage them in social responsibility. Protection of flora and fauna. They created a fund to support all types of environmental and social activities in which they allocate 0. 05% of their total annual revenue. One interesting idea is the Six Senses guest carbon- neutral program through which clients are enticed to donate money to help compensate the emission of carbon dioxide (CO? ) that the plane that brought them to the island produced. That fund is then distributed to NGOs that care about the reforestation of the planet. Preserving the environment with the ECHO program (Environmentally Conscious Hospitality Operations) through eco-friendly guidelines to all hotels and associates through the â€Å"reduce-reuse-recycle† process†. ITC India ITC is leading hotel in India for sustainability development. It has come up with Innovative designs, Water efficient buildings, Material resources and energy conservation steps in its various hotels . At 170,000 sq feet, ITC Green Centre is the world’s largest 0% water discharge, noncommercial Green building, and compared to similar buildings, ITC Green Centre has a 30% smaller carbon footprint. ITC is developing its hotel based on this building model and architecture. References Jauhari, Vinnie (Editor). International Journal of Contemporary Hospitality Management, Volume 19, Issue 5 : The Hospitality Industry in India. Bradford, , GBR: Emerald Group Publishing Ltd, 2007. p 364. Saxena, Atul. New Trends in Tourism and Hotel Industry. Delhi, IND: Global Media, 2008. p 191. Brody, Derrick. Latest Trends in Hotel Industry. Delhi, , IND: Global Media, 2009. p 4. Mannan, B. A..

Estimation of Tranexamic Acid Andethamsylate Using RP-HPLC

Estimation of Tranexamic Acid Andethamsylate Using RP-HPLC Chapter-3 Experimental work 3. EXPERIMENTAL WORK 3.1 MATERIALS AND METHODS Table 2. List of Chemical and standers used S.No Chemicals Manufacturer Name Grade 1 Water Processed in Bright Labs HPLC grade 2 Acetonitrile Fisher scientific HPLC grade 3 Orthophosphoric acid Merck GR grade 4 Tranexamic acid Sun pharma ltd BP 5 Ethamsylate Sun pharma ltd USP 6 KH2PO4 Merck GR grade 7 K2HPO4 Merck GR grade 8 Methanol Merck HPLC grade Table 3. List of instruments used S.No Instrumentname Model Number Soft Ware Manufacturers name 1 HPLC-auto sampler-UV detector ACME9000 Auto crome 3000 Youngline 2 Electronic balance Lab India 3 Sonicator CWUC9L 201402822 Spectrum tek 4 Vacuum Pump 28965405-289717 Vacuubrand 5 0.45 µ filter paper HPLC grade Rankem 3.2. Method development for the simultaneous estimation of Tranexamic acid andethamsylate by using RP-HPLC. Selection of mobile phase Selection of detectionwavelength Selection of column Selection of solvent delivery system Selection of flow rate Selection of column temperature Selection of diluent Selection of test concentration and injection volume 3.2.1. Selection of mobile phase Phosphate Buffer: Methanol (30:70) 3.2.2. Selection of wavelength 10mg Tranexamic acid and Ethamsylate were dissolved in mobile phase. The overlay spectrum was used for selection of wavelength for Tranexamic acid and Ethamsylate The iso-bestic point was taken as detection wavelength 286nm. 3.2.3. Selection of column Heart of HPLC made of 316 grade stainless steel packed with stationary phase. Silica based columns with different cross linking’s in the increasing order of polarity are as follows: à ¯Ã†â€™Ã… ¸- Non-polar-moderately polarPolar-à ¯Ã†â€™Ã‚   C1886 In reverse phase chromatography, hydrophobic interaction between drug molecule and the alkyl chains on the column packing material. Column is selected based on solubility, polarity chemical differences among analytes and Column selected: i.e. X-Bridge C18 (150 Ãâ€" 4.6 mm, packed with 5  µm), particle size Reasons: Better separation, Good tailing factor. 3.2.4. Selection of solvent delivery system Always preferable solvent delivery system. More chance of getting reproducible result on retention time of analytes. More economic than gradient technique. 3.2.5. Selection of flow rate Acceptable limit: Not more than 2.5 ml/min Flow rate selected was 1.0ml/min Flow rate is selected based on 1. Retention time 2. Column back pressure 3. Peak symmetry. 4. Separation of impurities. Reasons: For earlier elution of analyte and elution of all impurities within 10 min Information from the reference method in literature. 3.2.6. Selection of diluent Selection of diluents is based on the solubility of the analyte Diluent selected: Phosphate Buffer: Methanol (30:70 % v/v) Reason: Analyte is soluble in acetonitrile and water. 3.2.7. Selection of column temperature Preferable temperature is ambient or room temperature. Reasons: To elute all impurities along with analyte with in 10 min of run time. Less retention time Good peak shape Higher theoretical plates. Good resolution. 3.2.8. Selection of test concentration and injection volume Test concentration is finalized after it is proved that API is completely extractable at the selected test concentration. Test concentration is fixed based upon the response of API peak at selected detector wavelength. Tranexamic Acid and Ethamsylate label claimed 25mg and 50 mg And the test concentration selected is 100ppm Injection volume selected is 20 µL. Reason: good peak area, retention time, peak symmetry Chromatographic trails for simultaneous estimation Tranexamic acid Ethamsylate TRIAL 1 Parameters Method Stationary phase (column) : Kromosil C18 (150 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 100% of Methanol Ph : 3.0  ± 0.02 Flow rate (ml/min) : 1.0 Run time (minutes) : 8.0 Column hotness ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 242 Drugs RT (min) : 2.91 4.42 Fig. 4: Trial 1 S.No. Name RT[min] Area[ µV*s] TP TF Resolution 1 Tranexamic Acid 2.9167 491583 7707.5 1.0833 0.0000 2 Ethamsylate 4.4227 1076649 10124.7 1.0124 5.3676 Sum 1568232 Observation: 100% Methanol used for this trial, flow rate was 1ml/min at ambient temperature. Faster elution of the analyte takes place . TRIAL 2 Parameters Method Stationary phase (column) : Inertsil C18 (250 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 30:70 (Methanol : water) Ph : 3.5  ± 0.02 Flow rate (ml/min) : 1.0 Run time (minutes) : 8.0 Column temperature ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 228 Drugs RT (min) : 2.81 5.34 Fig. 5: Trial 2 S.No. Name RT[min] Area[ µV*s] TP TF Resolution 1 Tranexamic Acid 2.8167 1272583 4707.5 1.0333 0.0000 2 Ethamsylate 5.3467 1952369 9124.7 1.0524 7.1376 Sum 3224952 Observation: Methanol and water was used in the ratio of 70:30. The flow rate was 1ml/min at ambient temperature.Couldn’t get consistent retention time TRIAL 3 Parameters Method Stationary phase (column) : Inertsil C18 (250 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 30:70 (Methanol : Phosphate Buffer) Ph : 3.0  ± 0.02 Flow rate (ml/min) : 1.0 Run time (minutes) : 15.0 Column temperature ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 236 Drugs RT (min) : 2.86 10.48 Fig. 6: Trial 3 S.No. Name RT[min] Area[ µV*s] TP TF Resolution 1 Tranexamic Acid 2.8627 407583 2307.5 1.2833 0.0000 2 Ethamsylate 10.4802 9792049 9901.7 1.3124 10.2646 Sum 10199632 Observation: Methanol and Phosphate Buffer used in the ratio of (30:70 ) Couldn’t get consistent retention time Discussion: The above trials indicating that RT for the drug was not constant and elution time was faster which not prefered for the analysis. TRAIL 4 Optimizing method Parameters Method Stationary phase (column) : X-Bridge C18 (150 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 30:70 (Phosphate Buffer : Methanol) pH : 3.2  ± 0.02 Flow rate (ml/min) : 1.0 Run time (minutes) : 8.0 Column temperature ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 286 Drugs RT (min) : 3.01 5.06 Fig. 7: Developed Chromatogram S.No. Name RT[min] Area[ µV*s] TP TF Resolution 1 Tranexamic Acid 3.0167 1574827 3707.5 1.0833 0.0000 2 Ethamsylate 5.0667 2779277 5124.7 1.0124 8.5376 Sum 4354104 Discussion: All the experiments were complete by the higher than developed method and the consequences were acceptable. Optimized chromatographic conditions for simultaneous estimation of Tranexamic Acid and Ethamsylate Trail 4: (Optimized Chromatographic Conditions) Parameters Method Stationary phase (column) : X-Bridge C18 (150 Ãâ€" 4.6 mm, packed with 5  µm) Mobile Phase : 30:70 (Phosphate Buffer : Methanol) PH : 3.2  ± 0.02 Flow rate : 1.0 Run time (min) : 8.0 Column temperature ( °C) : Ambient Volume of injection loop (à ¯Ã‚ Ã‚ ­l) : 20 Detection wavelength (nm) : 286 Drugs RT (min) : 3.01 5.06 Assay procedure Preparation of 0.2M phosphate buffer: Buffer solution prepares by dissolving 2.72g of Potassium dihydrogen ortho phosphate (KH2PO4) in 1L of water and the degassing of the solution. Diluents Preparation: 1L of diluents was prepared by mixing 300 ml of 0.02 M Phosphate Buffer and 700 ml of Methanol. Preparation of stock solution: Accurately weighed 10 mg of the both Tranexamic Acid and Ethamsylate is transferred to 10 ml fresh and dry volumetric flask. The amount was making up to the mark among the Methanol and mixed well. This yielded a stock solution with concentration 1000 ppm of Tranexamic Acid and Ethamsylate mixture. Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the Tranexamic Acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Then compose up the amount up to the mark among the diluents and mix well. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of Tranexamic Acid and Ethamsylate respectively. Procedure 20à ¯Ã‚ Ã‚ ­Lof the standard and sample was injected into the chromatographic system and areas for the Tranexamic acid and Ethamsylate from the peaks were used for calculating the % assay by using the formulae. Assay calculation AT WS DT P Avg. Wt Assay % = x -x x -x 100 AS DS WT 100 Label Claim Where: AT = Average area counts of sample preparation. AS = Average area counts of standard preparation. WS=Weight of working standard taken in mg. P= Percentage purity of working standard LC = Label Claim of Tranexamic acid , Ethamsylate mg/ml. 3.4 METHOD VALIDATION 3.4.1 ANALYTICAL METHOD VALIDATION Validation parameters Specificity Linearity Range Accuracy Precision System precision Repeatability Intermediate Precision Detection Limit Quantitation Limit Robustness 1. Specificity The system suitability for specificity was carried out to determine whether there are any interference of any impurities in retention time of analytical peak. The study was performed by injecting blank. 2. Linearity The linearity is a systematic method its ability (within a given range) to get assessment results, which are directly relative to the absorption (amount) of analyte in sample. Preparation of standard stock solution: Accurately weighed 10 mg of the both tranexamic acid and Ethamsylate was transferred in to 10 ml fresh and dry volumetric flask. After that the amount was made up to the mark with the Methanol and mix well. This yielded a stock solution amid attention 1000 ppm of tranexamic acid with Ethamsylate mixture. Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock was transferred to 10 ml clean and dry volumetric flask. Then the volume was made up to the mark with the diluent and mixed well. This yielded a standard stock solution with concentrations of 25ppm and 25ppm of tranexamic acid and Ethamsylate respectively10 Procedure: Prepared a series of standard solutions not less than five during the particular concentration range along with investigate them like for each method. Acceptance criteria: The correlation coefficient should be not less than 0.9990 3. Range The range of a systematic process is the gap between the superior and lower concentration of analyte in sample for which it has been established to the investigative practice was a suitable level of accuracy, precision and linearity. Acceptance criteria: Linearity, Precision and Recovery should be shown. The logic behind this parameter was – typical concentration range was essential between which the actual concentration should fall when performing real sample analysis.10 4. Accuracy Preparation of standard stock solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transfer to 10 ml fresh and dried volumetric flask. Make up the volume up to mark with the diluents and mix well. The standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Method procedure: Prepared solutions in triplicate at levels 80%, 100% and 120s% of test concentrations using for tranexamic acid and Ethamsylate working Standards as per the test method and injected each solution in triplicate. Sample Are 100 % Recovery = x x 100 Standared Area conc. in % Accuracy normally refers to the difference between the mean of the set of results and the true or correct value for the quantity measured. According to IUPAC accuracy relates to the difference between results (or mean) and the true value. For analytical methods, there are two possible ways of determining the accuracy, absolute method and comparative method. Accuracy is best reported as percentage bias, which is calculated from the expression Procedure: Known amount of drug substance spiked with known amount of standard drug- minimum of three levels (80%, 100% 120% of test concentration), each level was triplicate. Acceptance criteria: Assay recovery should be between 97%-103%.10 5. Precision Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Subsequently make up the volume up to the mark among the diluent and well mixed. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Method precision: Six individual preparations were prepared using single batch of tranexamic acid and Ethamsylate functioning standard as for each test process and injected each one solutions. Injection precision: Solo preparation was prepared using single batch of Tranexamic acid and Ethamsylate effective standard as for each urbanized process in addition to injected six injections10. Acceptance Criteria: 1. RSD should not be more than 2.0% for five replicate injections of standard. 6. Ruggedness Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Subsequently make up the quantity up to the mark among the diluents and well mix. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Method Procedure: The standard solution was individually prepared as per the test method and injected each solution in six times using different system, analyst, and date. Acceptance Criteria: Overall RSD should not be more than 2.0 %. 7. Limit detection and limit of quantitation LOD: Lowest amount of analyte in a sample that can be detected but not necessarily quanities, under the stated experimental conditions. Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Then build up the quantity up to the mark with the diluents and mix well. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of Tranexamic acid and Ethamsylate respectively. Method Procedure: The mobile phase was permissible to run equilibrate with stationary phase up to good baseline was obtained. The different concentration ranging from 0.01 to 0.1ppm of tranexamic acid and 0.01 to 0.1ppm Ethamsylate was injected and peaks were recorded. 0.03 and 0.03ppm for tranexamic acid and Ethamsylate concentrations were detected respectively. LOD can be calculated based on signal-noise ratio,by using following formula LOD = S/N Where, S = Signal Obtained From LOD Solution. N = Average Baseline Noise Obtained from Blank Acceptance criteria for LOD and LOQ RSD Criteria Concentration at which RSD Concentration at which RSD 8. Robustness Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. After that make up the quantity up to the mark with diluent and well mixed. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Method procedure: 1. Flow: The standard solution was prepared and injected for the two times with (+1) flow rate. 2. Mobile Phase: The standard solution was prepared and injected for the two times with (+5) Mobile Phase composition. Appraise of its capability to remain unchanged by minute, but conscious variations in process parameters and provides signal of its reliability during its normal usage. Procedure: samples were analyzed under the following conditions.10 3. Stability studies In the rational design and evaluation of dosage forms for the drugs, the stability of the activity components must be a major criterion in determining their stability. The medicine has to reach the patient in an active and acceptable form maintaining the criteria for acceptable equality. The quality of the product has to be retained as long as the product is offered for sale or for administration to the patient. 10 Acceptance Criteria: Overall RSD should not be more than 2.0 %. 9. System suitability Preparation of standard solution: Accurately amount of 0.25 and 0.25 ml of the tranexamic acid and Ethamsylate stock solution transferred to 10 ml clean and dried volumetric flask. Subsequently make up the amount up to the mark with diluent and well mixed. Finally the standard stock solution with concentrations of 25 ppm and 25 ppm of tranexamic acid and Ethamsylate respectively. Procedure: Standard solution was prepared and injected six times to test the performance of the chromatographic instrument. Acceptance Criteria: 1. RSD should not be more than 2.0% for five replicate injections of standard 2. USP Tailing for tranexamic acid and Ethamsylate peak in not more than 2.0 3. The column efficiency as determined for tranexamic acid and ethamsylate Plate Count should not be more than 2000. Dept.of Pharmaceutical Analysis JNTUA-OTRI, Ananthapuramu Page 1